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Polyglutamine Repeats Are Associated to Specific Sequence Biases That Are Conserved among Eukaryotes
Nine human neurodegenerative diseases, including Huntington's disease and several spinocerebellar ataxia, are associated to the aggregation of proteins comprising an extended tract of consecutive glutamine residues (polyQs) once it exceeds a certain length threshold. This event is believed to b...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3270027/ https://ncbi.nlm.nih.gov/pubmed/22312432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030824 |
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