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Mechanisms for the inhibition of amyloid aggregation by small ligands

The formation of amyloid aggregates is the hallmark of systemic and neurodegenerative disorders, also known as amyloidoses. Many proteins have been found to aggregate into amyloid-like fibrils and this process is recognized as a general tendency of polypeptides. Lysozyme, an antibacterial protein, i...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Ramazzotti, Matteo, Melani, Fabrizio, Marchi, Laura, Mulinacci, Nadia, Gestri, Stefano, Tiribilli, Bruno, Degl'Innocenti, Donatella
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041158/
https://ncbi.nlm.nih.gov/pubmed/27512096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20160101
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