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Non-steroidal Anti-inflammatory Drugs Inhibit Calpain Activity and Membrane Localization of Calpain 2 Protease

Non-steroidal anti-inflammatory drugs (NSAIDs) are used frequently worldwide for the alleviation of pain despite their capacity to cause adverse gastrointestinal (GI) side effects. GI toxicity, once thought to be the result of non-specific inhibition of cyclooxegenase (COX) enzymes, is now hypothesi...

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Detalhes bibliográficos
Main Authors: Silver, Kristopher, Leloup, Ludovic, Freeman, Lisa C., Wells, Alan, Lillich, James D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269911/
https://ncbi.nlm.nih.gov/pubmed/20854926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2010.09.007
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