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Depolarization and decreased surface expression of K(+) channels contribute to NSAID-inhibition of intestinal restitution

Non-steroidal anti-inflammatory drugs (NSAIDs) contribute to gastrointestinal ulcer formation by inhibiting epithelial cell migration and mucosal restitution; however, the drug-affected signaling pathways are poorly defined. We investigated whether NSAID inhibition of intestinal epithelial migration...

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Detalles Bibliográficos
Main Authors: Freeman, LC, Narvaez, DF, McCoy, A, von Stein, FB, Young, S, Silver, K, Ganta, S., Koch, D, Hunter, R, Gilmour, RF, Lillich, JD
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269908/
https://ncbi.nlm.nih.gov/pubmed/17499219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2007.03.030
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