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Drosophila topoisomerase I: isolation, purification and characterization.

We have purified and characterized topoisomerase I from Drosophila melanogaster. The molecular weight of the enzyme is 135,000; 100,000, 90,000, and 65,000 molecular weight products result from degradation of the enzyme. The enzyme relaxes both positive and negative supercoiled DNA. Mg++ is not abso...

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Détails bibliographiques
Auteurs principaux: Javaherian, K, Tse, Y C, Vega, J
Format: Artigo
Langue:Inglês
Publié: 1982
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC326976/
https://ncbi.nlm.nih.gov/pubmed/6294622
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