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Drosophila topoisomerase I: isolation, purification and characterization.

We have purified and characterized topoisomerase I from Drosophila melanogaster. The molecular weight of the enzyme is 135,000; 100,000, 90,000, and 65,000 molecular weight products result from degradation of the enzyme. The enzyme relaxes both positive and negative supercoiled DNA. Mg++ is not abso...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Javaherian, K, Tse, Y C, Vega, J
Format: Artigo
Language:Inglês
Published: Oxford University Press 1982
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC326976/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6294622/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/10.21.6945
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