Drosophila topoisomerase I: isolation, purification and characterization.

We have purified and characterized topoisomerase I from Drosophila melanogaster. The molecular weight of the enzyme is 135,000; 100,000, 90,000, and 65,000 molecular weight products result from degradation of the enzyme. The enzyme relaxes both positive and negative supercoiled DNA. Mg++ is not abso...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Javaherian, K, Tse, Y C, Vega, J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1982
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC326976/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6294622/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/10.21.6945
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