p38 Mitogen-Activated Protein Kinase and Liver X Receptor-α Mediate the Leptin Effect on Sterol Regulatory Element Binding Protein-1c Expression in Hepatic Stellate Cells

Leptin, a key hormone in regulating energy homeostasis, is mainly produced by adipocytes. Cogent evidence indicates a unique role of leptin in the promotion of liver fibrosis. Hepatic stellate cell (HSC) activation is a pivotal step in the process of liver fibrosis. Sterol regulatory element binding...

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Main Authors: Yan, Kunfeng, Deng, Xiong, Zhai, Xuguang, Zhou, Mingming, Jia, Xin, Luo, Lin, Niu, Minghui, Zhu, Huixia, Qiang, Hui, Zhou, Yajun
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269638/
https://ncbi.nlm.nih.gov/pubmed/21979752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00243
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