Suppression of EAE and Prevention of Blood-Brain Barrier Breakdown after Vaccination with Novel Bifunctional Peptide Inhibitor

The efficacy of bifunctional peptide inhibitor (BPI) in preventing blood-brain barrier (BBB) breakdown during onset of experimental autoimmune encephalomyelitis (EAE) and suppression of the disease was evaluated in mice. The mechanism that defines how BPI prevents the disease was investigated by mea...

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Bibliographic Details
Main Authors: Badawi, Ahmed H., Kiptoo, Paul, Wang, Wen-Tung, Choi, In-Young, Lee, Phil, Vines, Charlotte M., Siahaan, Teruna J.
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269550/
https://ncbi.nlm.nih.gov/pubmed/22210333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2011.12.013
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