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An Integrated Stochastic Model of ‘Inside-Out’ Integrin Activation and Selective T Lymphocyte Recruitment

The pattern of T lymphocyte homing is hypothesized to be controlled by combnations of chemokine receptors and complementary chemokines. Here, we use numerical simulation to explore the relationship among chemokine potency and concentration, signal transduction, and adhesion. We have developed a form...

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Autori principali: Beste, Michael T., Lee, Dooyoung, King, Michael R., Koretzky, Gary A., Hammer, Daniel A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269544/
https://ncbi.nlm.nih.gov/pubmed/22149624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/la203803e
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