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An Integrated Stochastic Model of ‘Inside-Out’ Integrin Activation and Selective T Lymphocyte Recruitment

The pattern of T lymphocyte homing is hypothesized to be controlled by combnations of chemokine receptors and complementary chemokines. Here, we use numerical simulation to explore the relationship among chemokine potency and concentration, signal transduction, and adhesion. We have developed a form...

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Detalhes bibliográficos
Main Authors: Beste, Michael T., Lee, Dooyoung, King, Michael R., Koretzky, Gary A., Hammer, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269544/
https://ncbi.nlm.nih.gov/pubmed/22149624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/la203803e
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