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Interference Between DNA Replication and Transcription as a Cause of Genomic Instability

Replication and transcription are key aspects of DNA metabolism that take place on the same template and potentially interfere with each other. Conflicts between these two activities include head-on or co-directional collisions between DNA and RNA polymerases, which can lead to the formation of DNA...

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Detalles Bibliográficos
Main Authors: Lin, Yea-Lih, Pasero, Philippe
Formato: Artigo
Idioma:Inglês
Publicado: Bentham Science Publishers 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269018/
https://ncbi.nlm.nih.gov/pubmed/22942676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138920212799034767
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