Overcoming Memory T cell Responses for Induction of Delayed Tolerance in Nonhuman Primates

The presence of alloreactive memory T cells is a major barrier for induction of tolerance in primates. In theory, delaying conditioning for tolerance induction until after organ transplantation could further decrease the efficacy of the regimen, since pre-existing alloreactive memory T cells might b...

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Main Authors: Yamada, Y., Boskovic, S., Aoyama, A., Murakami, T., Putheti, P., Smith, R. N., Ochiai, T., Nadazdin, O., Koyama, I., Boenisch, O., Najafian, N., Bhasin, M.K., Colvin, R. B., Madsen, J. C., Strom, T. B., Sachs, D. H., Benichou, G., Cosimi, A. B., Kawai, T.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268945/
https://ncbi.nlm.nih.gov/pubmed/22053723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2011.03795.x
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