High Risk of Benzo[α]pyrene-induced Lung Cancer in E160D FEN1 Mutant Mice

Flap endonuclease 1 (FEN1), a member of the Rad2 nuclease family, possesses 5’ flap endonuclease (FEN), 5’ exonuclease (EXO), and gap-endonuclease (GEN) activities. The multiple, structure-specific nuclease activities of FEN1 allow it to process different intermediate DNA structures during DNA repli...

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Bibliografiset tiedot
Päätekijät: Wu, Zhenxing, Lin, Yuanji, Xu, Hong, Dai, Huifang, Zhou, Mian, Tsao, Sharlene, Zheng, Li, Shen, Binghui
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268909/
https://ncbi.nlm.nih.gov/pubmed/22155171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2011.11.009
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