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Genetic ablation of the GluK4 kainate receptor subunit causes anxiolytic and antidepressant-like behavior in mice

There is a clear link between dysregulation of glutamatergic signaling and mood disorders. Genetic variants in the glutamate receptor gene GRIK4, which encodes the kainate receptor subunit GluK4, alter the susceptibility for depression, bipolar disorder and schizophrenia. Here we demonstrate that Gr...

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Detalhes bibliográficos
Main Authors: Catches, Justin S., Xu, Jian, Contractor, Anis
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268896/
https://ncbi.nlm.nih.gov/pubmed/22203159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2011.12.026
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