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Differentiation stage determines pathologic and protective allergen-specific CD4+ T cell outcomes during specific immunotherapy

BACKGROUND: The main obstacle to elucidating the role of CD4(+) T cells in allergen-specific immunotherapy has been the absence of an adequately sensitive approach to directly characterize rare allergen-specific T cells without introducing substantial phenotypic modifications by in vitro amplificati...

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Detalhes bibliográficos
Main Authors: Wambre, Erik, DeLong, Jonathan H., James, Eddie A., LaFond, Rebecca E., Robinson, David, Kwok, William W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268867/
https://ncbi.nlm.nih.gov/pubmed/21975176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2011.08.034
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