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Specific immunotherapy modifies allergen-specific CD4+ T cell responses in an epitope-dependent manner

BACKGROUND: Understanding the mechanisms by which the immune system induces and controls allergic inflammation at the T cell epitope level is critical for the design of new allergy vaccine strategies. OBJECTIVE: To characterize allergen-specific T cell responses linked with allergy or peripheral tol...

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Detalhes bibliográficos
Main Authors: Wambre, Erik, DeLong, Jonathan H., James, Eddie A., Torres-Chinn, Nadia, Pfützner, Wolfgang, Möbs, Christian, Durham, Stephen R., Till, Stephen J., Robinson, David, Kwok, William W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961577/
https://ncbi.nlm.nih.gov/pubmed/24373351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2013.10.054
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