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High sequence specificity of micrococcal nuclease.

The substrate specificity of micrococcal nuclease (EC 3.1.4.7.) has been studied. The enzyme recognises features of nucleotide composition, nucleotide sequence and tertiary structure of DNA. Kinetic analysis indicates that the rate of cleavage is 30 times greater at the 5' side of A or T than a...

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Bibliografiske detaljer
Main Authors: Dingwall, C, Lomonossoff, G P, Laskey, R A
Format: Artigo
Sprog:Inglês
Udgivet: 1981
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC326883/
https://ncbi.nlm.nih.gov/pubmed/6269057
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