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High sequence specificity of micrococcal nuclease.

The substrate specificity of micrococcal nuclease (EC 3.1.4.7.) has been studied. The enzyme recognises features of nucleotide composition, nucleotide sequence and tertiary structure of DNA. Kinetic analysis indicates that the rate of cleavage is 30 times greater at the 5' side of A or T than a...

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Autors principals: Dingwall, C, Lomonossoff, G P, Laskey, R A
Format: Artigo
Idioma:Inglês
Publicat: 1981
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC326883/
https://ncbi.nlm.nih.gov/pubmed/6269057
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