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Dark Matter: Are Mice the Solution to Missing Heritability?

Genome-wide association studies (GWAS) in humans have identified hundreds of single nucleotide polymorphisms associated with complex traits, yet for most traits studied, the sum total of all these identified variants fail to explain a significant portion of the heritable variation. Reasons for this...

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Detalhes bibliográficos
Main Authors: Parker, Clarissa C., Palmer, Abraham A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268586/
https://ncbi.nlm.nih.gov/pubmed/22303328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2011.00032
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