FOLFIRI Plus Bevacizumab 5 mg/kg Versus 10 mg/kg as Second-line Therapy in Patients with Metastatic Colorectal Cancer Who Have Failed First-line Bevacizumab Plus Oxaliplatin-based Therapy: A Randomized Phase III Study (EAGLE Study)

We planned a multicenter randomized phase III study to evaluate the efficacy of appropriate dose of bevacizumab (5 or 10 mg/kg) with FOLFIRI in patients with advanced/metastatic colorectal cancer who have failed prior bevacizumab plus oxaliplatin-based therapy. The primary endpoint is progression-fr...

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Detalhes bibliográficos
Main Authors: Mishima, Hideyuki, Oba, Koji, Sakamoto, Junichi, Muro, Kei, Yoshino, Takayuki, Hyodo, Ichinosuke, Maehara, Yoshihiko
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
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Clinical Trial Notes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268463/
https://ncbi.nlm.nih.gov/pubmed/22167662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jjco/hyr180
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