Molecular Cloning of a Xylosyltransferase That Transfers the Second Xylose to O-Glucosylated Epidermal Growth Factor Repeats of Notch

The extracellular domain of Notch contains epidermal growth factor (EGF) repeats that are extensively modified with different O-linked glycans. O-Fucosylation is essential for receptor function, and elongation with N-acetylglucosamine, catalyzed by members of the Fringe family, modulates Notch activ...

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Autores principales: Sethi, Maya K., Buettner, Falk F. R., Ashikov, Angel, Krylov, Vadim B., Takeuchi, Hideyuki, Nifantiev, Nikolay E., Haltiwanger, Robert S., Gerardy-Schahn, Rita, Bakker, Hans
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Glycobiology and Extracellular Matrices
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268431/
https://ncbi.nlm.nih.gov/pubmed/22117070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.302406
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