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p38α Mediates Cell Survival in Response to Oxidative Stress via Induction of Antioxidant Genes: EFFECT ON THE p70S6K PATHWAY
We reveal a novel pro-survival role for mammalian p38α in response to H(2)O(2), which involves an up-regulation of antioxidant defenses. The presence of p38α increases basal and H(2)O(2)-induced expression of the antioxidant enzymes: superoxide-dismutase 1 (SOD-1), SOD-2, and catalase through differ...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3268422/ https://ncbi.nlm.nih.gov/pubmed/22139847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.323709 |
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