Core Fucosylation of μ Heavy Chains Regulates Assembly and Intracellular Signaling of Precursor B Cell Receptors

α1,6-Fucosyltransferase (Fut8) knock-out (Fut8(−/−)) mice showed an abnormality in pre-B cell generation. Membrane assembly of pre-BCR is a crucial checkpoint for pre-B cell differentiation and proliferation in both humans and mice. The assembly of pre-BCR on the cell surface was substantially block...

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Dades bibliogràfiques
Autors principals: Li, Wenzhe, Liu, Qingping, Pang, Yue, Jin, Jinhua, Wang, Huiguo, Cao, Hongyu, Li, Zhi, Wang, Xu, Ma, Biao, Chi, Yan, Wang, Renjun, Kondo, Akihiro, Gu, Jianguo, Taniguchi, Naoyuki
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Glycobiology and Extracellular Matrices
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268410/
https://ncbi.nlm.nih.gov/pubmed/22084235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.303123
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