Novel Mechanistic Link between Focal Adhesion Remodeling and Glucose-stimulated Insulin Secretion

Actin cytoskeleton remodeling is well known to be positively involved in glucose-stimulated pancreatic β cell insulin secretion. We have observed glucose-stimulated focal adhesion remodeling at the β cell surface and have shown this to be crucial for glucose-stimulated insulin secretion. However, th...

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Hlavní autoři: Rondas, Dieter, Tomas, Alejandra, Soto-Ribeiro, Martinho, Wehrle-Haller, Bernhard, Halban, Philippe A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268403/
https://ncbi.nlm.nih.gov/pubmed/22139838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.279885
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