Critical role for phosphoinositide 3-kinase gamma in parasite invasion and disease progression of cutaneous leishmaniasis

Obligate intracellular pathogens such as Leishmania specifically target host phagocytes for survival and replication. Phosphoinositide 3-kinase γ (PI3Kγ), a member of the class I PI3Ks that is highly expressed by leukocytes, controls cell migration by initiating actin polymerization and cytoskeletal...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Cummings, Hannah E., Barbi, Joseph, Reville, Patrick, Oghumu, Steve, Zorko, Nicholas, Sarkar, Anasuya, Keiser, Tracy L., Lu, Bao, Rückle, Thomas, Varikuti, Sanjay, Lezama-Davila, Claudio, Wewers, Mark D., Whitacre, Caroline, Radzioch, Danuta, Rommel, Christian, Seveau, Stéphanie, Satoskar, Abhay R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268302/
https://ncbi.nlm.nih.gov/pubmed/22232690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1110339109
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados