PI3Kgamma (PI3Kγ) is essential for efficient induction of CXCR3 on activated T cells

The gamma isoform of PI3Kinase (PI3Kγ) controls leukocyte chemotaxis by participating in GPCR signaling, and by regulating cellular polarization. Here we show that PI3Kγ is required for efficient induction of CXC chemokine receptor 3 (CXCR3) on T cells upon activation. T cells from PI3Kγ(−/−) mice u...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Barbi, Joseph, Cummings, Hannah E., Lu, Bao, Oghumu, Steve, Rückle, Thomas, Rommel, Christian, Lafuse, William, Whitacre, Caroline C., Satoskar, Abhay R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Chemokines, Cytokines, and Interleukins
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2569163/
https://ncbi.nlm.nih.gov/pubmed/18658026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-02-135715
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados