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Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand T(fh) cells and promote germinal center induction

For subunit vaccines, adjuvants play a key role in shaping immunological memory. Nanoparticle (NP) delivery systems for antigens and/or molecular danger signals are promising adjuvants capable of promoting both cellular and humoral immune responses, but in most cases the mechanisms of action of thes...

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Autori principali: Moon, James J., Suh, Heikyung, Li, Adrienne V., Ockenhouse, Christian F., Yadava, Anjali, Irvine, Darrell J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268296/
https://ncbi.nlm.nih.gov/pubmed/22247289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112648109
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