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Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand T(fh) cells and promote germinal center induction
For subunit vaccines, adjuvants play a key role in shaping immunological memory. Nanoparticle (NP) delivery systems for antigens and/or molecular danger signals are promising adjuvants capable of promoting both cellular and humoral immune responses, but in most cases the mechanisms of action of thes...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3268296/ https://ncbi.nlm.nih.gov/pubmed/22247289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112648109 |
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