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Cardiac dysfunction in adipose triglyceride lipase deficiency: treatment with a PPARα agonist

BACKGROUND AND PURPOSE: Adipose triglyceride lipase (ATGL) has been identified as a rate-limiting enzyme of mammalian triglyceride catabolism. Deletion of the ATGL gene in mice results in severe lipid accumulation in a variety of tissues including the heart. In the present study we investigated card...

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Detalhes bibliográficos
Main Authors: Wölkart, G, Schrammel, A, Dörffel, K, Haemmerle, G, Zechner, R, Mayer, B
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268192/
https://ncbi.nlm.nih.gov/pubmed/21585347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01490.x
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