Role of the ubiquitin–proteasome system in cardiac dysfunction of adipose triglyceride lipase-deficient mice

Systemic deletion of the gene encoding for adipose triglyceride lipase (ATGL) in mice leads to severe cardiac dysfunction due to massive accumulation of neutral lipids in cardiomyocytes. Recently, impaired peroxisome proliferator-activated receptor α (PPARα) signaling has been described to substanti...

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Detalhes bibliográficos
Publicado no:J Mol Cell Cardiol
Main Authors: Mussbacher, Marion, Stessel, Heike, Wölkart, Gerald, Haemmerle, Guenter, Zechner, Rudolf, Mayer, Bernd, Schrammel, Astrid
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263609/
https://ncbi.nlm.nih.gov/pubmed/25285770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.09.028
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