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Role of the ubiquitin–proteasome system in cardiac dysfunction of adipose triglyceride lipase-deficient mice

Systemic deletion of the gene encoding for adipose triglyceride lipase (ATGL) in mice leads to severe cardiac dysfunction due to massive accumulation of neutral lipids in cardiomyocytes. Recently, impaired peroxisome proliferator-activated receptor α (PPARα) signaling has been described to substanti...

詳細記述

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書誌詳細
出版年:J Mol Cell Cardiol
主要な著者: Mussbacher, Marion, Stessel, Heike, Wölkart, Gerald, Haemmerle, Guenter, Zechner, Rudolf, Mayer, Bernd, Schrammel, Astrid
フォーマット: Artigo
言語:Inglês
出版事項: Academic Press 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263609/
https://ncbi.nlm.nih.gov/pubmed/25285770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2014.09.028
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