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Using Parametric Multipoint Lods and Mods for Linkage Analysis Requires a Shift in Statistical Thinking
Multipoint (MP) linkage analysis represents a valuable tool for whole-genome studies but suffers from the disadvantage that its probability distribution is unknown and varies as a function of marker information and density, genetic model, number and structure of pedigrees, and the affection status d...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
S. Karger AG
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3267993/ https://ncbi.nlm.nih.gov/pubmed/22189469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000331463 |
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