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Using Parametric Multipoint Lods and Mods for Linkage Analysis Requires a Shift in Statistical Thinking

Multipoint (MP) linkage analysis represents a valuable tool for whole-genome studies but suffers from the disadvantage that its probability distribution is unknown and varies as a function of marker information and density, genetic model, number and structure of pedigrees, and the affection status d...

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Detalhes bibliográficos
Main Authors: Hodge, Susan E., Baskurt, Zeynep, Strug, Lisa J.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267993/
https://ncbi.nlm.nih.gov/pubmed/22189469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000331463
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