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Effects of Pathogenic Proline Mutations on Myosin Assembly

Laing distal myopathy (MPD1) is a genetically dominant myopathy characterized by early and selective weakness of the distal muscles. Mutations in the MYH7 gene encoding for the β-myosin heavy chain are the underlying genetic cause of MPD1. However, their pathogenic mechanisms are currently unknown....

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Bibliografische gegevens
Hoofdauteurs: Buvoli, Massimo, Buvoli, Ada, Leinwand, Leslie A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267876/
https://ncbi.nlm.nih.gov/pubmed/22155079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.11.042
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