SOX2 expression correlates with lymph-node metastases and distant spread in right-sided colon cancer

BACKGROUND: The transcription factor SOX2, which is involved in the induction of pluripotent stem cells and contributes to colorectal carcinogenesis, is associated with a poor prognosis in colon cancer (CC). Furthermore, SOX2 is a repressor of the transcriptional activity of β-catenin in vitro. Sinc...

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Autors principals: Neumann, Jens, Bahr, Fiorina, Horst, David, Kriegl, Lydia, Engel, Jutta, Luque, Raquel Mejias, Gerhard, Markus, Kirchner, Thomas, Jung, Andreas
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267776/
https://ncbi.nlm.nih.gov/pubmed/22168803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-518
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