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pitx2 Deficiency Results in Abnormal Ocular and Craniofacial Development in Zebrafish
Human PITX2 mutations are associated with Axenfeld-Rieger syndrome, an autosomal-dominant developmental disorder that involves ocular anterior segment defects, dental hypoplasia, craniofacial dysmorphism and umbilical abnormalities. Characterization of the PITX2 pathway and identification of the mec...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3267762/ https://ncbi.nlm.nih.gov/pubmed/22303467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030896 |
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