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pitx2 Deficiency Results in Abnormal Ocular and Craniofacial Development in Zebrafish

Human PITX2 mutations are associated with Axenfeld-Rieger syndrome, an autosomal-dominant developmental disorder that involves ocular anterior segment defects, dental hypoplasia, craniofacial dysmorphism and umbilical abnormalities. Characterization of the PITX2 pathway and identification of the mec...

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Hlavní autoři: Liu, Yi, Semina, Elena V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267762/
https://ncbi.nlm.nih.gov/pubmed/22303467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030896
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