Transgenic overexpression of keratinocyte-specific VEGF and Ang1 in combination promotes wound healing under nondiabetic but not diabetic conditions

VEGF and Angiopoietin (Ang)1 are growth factors that independently improve wound healing outcomes. Using a tet-repressible mouse model coupled with streptozotocin-induced diabetes, we examined wound healing in diabetic and nondiabetic mice engineered to overexpress keratinocyte-specific (K5) VEGF, A...

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Detalhes bibliográficos
Main Authors: Loyd, Candace M, Diaconu, Doina, Fu, Wen, Adams, Gregory N, Brandt, Erin, Knutsen, Dorothy A, Wolfram, Julie A, McCormick, Thomas S, Ward, Nicole L
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267480/
https://ncbi.nlm.nih.gov/pubmed/22295141
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