Formulation and Evaluation of a Sustained-Release Tablets of Metformin Hydrochloride Using Hydrophilic Synthetic and Hydrophobic Natural Polymers

Metformin hydrochloride has relatively short plasma half-life, low absolute bioavailability. The need for the administration two to three times a day when larger doses are required can decrease patient compliance. Sustained release formulation that would maintain plasma level for 8-12 h might be suf...

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Bibliografske podrobnosti
Main Authors: Wadher, K. J., Kakde, R. B., Umekar, M. J.
Format: Artigo
Jezik:Inglês
Izdano: Medknow Publications & Media Pvt Ltd 2011
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267306/
https://ncbi.nlm.nih.gov/pubmed/22303065
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