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Distinct evolutionary strategies of human leucocyte antigen loci in pathogen-rich environments

Human leucocyte antigen (HLA) loci have a complex evolution where both stochastic (e.g. genetic drift) and deterministic (natural selection) forces are involved. Owing to their extraordinary level of polymorphism, HLA genes are useful markers for reconstructing human settlement history. However, HLA...

詳細記述

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書誌詳細
主要な著者: Sanchez-Mazas, Alicia, Lemaître, Jean-François, Currat, Mathias
フォーマット: Artigo
言語:Inglês
出版事項: The Royal Society 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267122/
https://ncbi.nlm.nih.gov/pubmed/22312050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2011.0312
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