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Biochemical Discrimination between Selenium and Sulfur 2: Mechanistic Investigation of the Selenium Specificity of Human Selenocysteine Lyase

Selenium is an essential trace element incorporated into selenoproteins as selenocysteine. Selenocysteine (Sec) lyases (SCLs) and cysteine (Cys) desulfurases (CDs) catalyze the removal of selenium or sulfur from Sec or Cys, respectively, and generally accept both substrates. Intriguingly, human SCL...

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Detalhes bibliográficos
Main Authors: Johansson, Ann-Louise, Collins, Ruairi, Arnér, Elias S. J., Brzezinski, Peter, Högbom, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266904/
https://ncbi.nlm.nih.gov/pubmed/22291978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030528
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