Reaction Mechanism and Molecular Basis for Selenium/Sulfur Discrimination of Selenocysteine Lyase

Selenocysteine lyase (SCL) catalyzes the pyridoxal 5′-phosphate-dependent removal of selenium from l-selenocysteine to yield l-alanine. The enzyme is proposed to function in the recycling of the micronutrient selenium from degraded selenoproteins containing selenocysteine residue as an essential com...

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Detalhes bibliográficos
Main Authors: Omi, Rie, Kurokawa, Suguru, Mihara, Hisaaki, Hayashi, Hideyuki, Goto, Masaru, Miyahara, Ikuko, Kurihara, Tatsuo, Hirotsu, Ken, Esaki, Nobuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852952/
https://ncbi.nlm.nih.gov/pubmed/20164179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.084475
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