Monocyte tissue factor–dependent activation of coagulation in hypercholesterolemic mice and monkeys is inhibited by simvastatin

Hypercholesterolemia is a major risk factor for atherosclerosis. It also is associated with platelet hyperactivity, which increases morbidity and mortality from cardiovascular disease. However, the mechanisms by which hypercholesterolemia produces a procoagulant state remain undefined. Atheroscleros...

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Bibliografiset tiedot
Päätekijät: Owens, A. Phillip, Passam, Freda H., Antoniak, Silvio, Marshall, Stephanie M., McDaniel, Allison L., Rudel, Lawrence, Williams, Julie C., Hubbard, Brian K., Dutton, Julie-Ann, Wang, Jianguo, Tobias, Peter S., Curtiss, Linda K., Daugherty, Alan, Kirchhofer, Daniel, Luyendyk, James P., Moriarty, Patrick M., Nagarajan, Shanmugam, Furie, Barbara C., Furie, Bruce, Johns, Douglas G., Temel, Ryan E., Mackman, Nigel
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2012
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266787/
https://ncbi.nlm.nih.gov/pubmed/22214850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI58969
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