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Notch pathway regulation of neural crest cell development in vivo

The function of Notch signaling in murine neural crest-derived cell lineages in vivo was examined. Conditional gain (Wnt1Cre;Rosa(Notch)) or loss (Wnt1Cre;RBP-J(f/f)) of Notch signaling in neural crest cells (NCCs) in vivo results in craniofacial, cardiac, and trunk abnormalities. Severe craniofacia...

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Detalhes bibliográficos
Main Authors: Mead, Timothy J., Yutzey, Katherine E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266628/
https://ncbi.nlm.nih.gov/pubmed/22275227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.23717
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