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Notch pathway regulation of chondrocyte differentiation and proliferation during appendicular and axial skeleton development

The role of Notch signaling in cartilage differentiation and maturation in vivo was examined. Conditional Notch pathway gain and loss of function was achieved using a Cre/loxP approach to manipulate Notch signaling in cartilage precursors and chondrocytes of the developing mouse embryo. Conditional...

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Detalhes bibliográficos
Main Authors: Mead, Timothy J., Yutzey, Katherine E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732875/
https://ncbi.nlm.nih.gov/pubmed/19590010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902306106
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