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Phospholipase Cγ2 is required for basal but not oestrogen deficiency–induced bone resorption

BACKGROUND: Osteoclasts play a critical role in bone resorption under basal conditions, but they also contribute to pathological bone loss during diseases including postmenopausal osteoporosis. Phospholipase Cγ2 (PLCγ2) is an important signalling molecule in diverse haematopoietic lineages. Here, we...

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Detalhes bibliográficos
Main Authors: Kertész, Zsuzsanna, Győri, Dávid, Körmendi, Szandra, Fekete, Tünde, Kis-Tóth, Katalin, Jakus, Zoltán, Schett, Georg, Rajnavölgyi, Éva, Dobó-Nagy, Csaba, Mócsai, Attila
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266491/
https://ncbi.nlm.nih.gov/pubmed/21749368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2362.2011.02556.x
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