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Heritable Transmission of Diabetic Metabolic Memory in Zebrafish Correlates With DNA Hypomethylation and Aberrant Gene Expression

Metabolic memory (MM) is the phenomenon whereby diabetes complications persist and progress after glycemic recovery is achieved. Here, we present data showing that MM is heritable and that the transmission correlates with hyperglycemia-induced DNA hypomethylation and aberrant gene expression. Strept...

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מידע ביבליוגרפי
Main Authors: Olsen, Ansgar S., Sarras, Michael P., Leontovich, Alexey, Intine, Robert V.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Diabetes Association 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266410/
https://ncbi.nlm.nih.gov/pubmed/22228713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0588
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