Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein–Coupled Receptor FFAR2

Interest in how the gut microbiome can influence the metabolic state of the host has recently heightened. One postulated link is bacterial fermentation of “indigestible” prebiotics to short-chain fatty acids (SCFAs), which in turn modulate the release of gut hormones controlling insulin release and...

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Bibliographic Details
Main Authors: Tolhurst, Gwen, Heffron, Helen, Lam, Yu Shan, Parker, Helen E., Habib, Abdella M., Diakogiannaki, Eleftheria, Cameron, Jennifer, Grosse, Johannes, Reimann, Frank, Gribble, Fiona M.
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2012
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266401/
https://ncbi.nlm.nih.gov/pubmed/22190648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1019
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