Fetal and Neonatal Goiter in Cynomolgus Monkeys Following Administration of the Antithyroid Drug Thiamazole at High Doses to Dams During Pregnancy

To evaluate morphologic alterations in the thyroid gland in the second generation in cynomolgus monkeys, pregnant dams were exposed to high doses of thiamazole. In Experiment A, dams received thiamazole intragastrically via a nasogastric catheter from gestation day (GD) 50 to GD 150 or on the day be...

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Autori principali: Yoshikawa, Tsuyoshi, Moriyama, Akiko, Kodama, Rinya, Sasaki, Yuji, Sunagawa, Tatsumi, Okazaki, Takanobu, Urashima, Asami, Nishida, Yoshiro, Arima, Akihiro, Inoue, Ayumi, Negishi, Takayuki, Yoshikawa, Yasuhiro, Ihara, Toshio, Maeda, Hiroshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Japanese Society of Toxicologic Pathology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266356/
https://ncbi.nlm.nih.gov/pubmed/22319233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.24.215
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