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Theoretical studies of the selective binding to DNA of two non-intercalating ligands: netropsin and SN 18071.

A theoretical study of the binding to DNA of netropsin and a bisquaternary ammonium heterocycle, SN 18071, is undertaken with an energy minimizing program based on empirical potential functions. The positioning of the ligand is achieved by force and torque calculations and its internal flexibility i...

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Publicat a:Nucleic Acids Res
Autors principals: Zakrzewska, K, Lavery, R, Pullman, B
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1983
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC326627/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6324104/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/11.24.8825
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