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Theoretical studies of the selective binding to DNA of two non-intercalating ligands: netropsin and SN 18071.

A theoretical study of the binding to DNA of netropsin and a bisquaternary ammonium heterocycle, SN 18071, is undertaken with an energy minimizing program based on empirical potential functions. The positioning of the ligand is achieved by force and torque calculations and its internal flexibility i...

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Detalhes bibliográficos
Main Authors: Zakrzewska, K, Lavery, R, Pullman, B
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC326627/
https://ncbi.nlm.nih.gov/pubmed/6324104
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